Serafim, A., Company, R., Lopes, B., Fonseca, V.F., França, S., Vasconcelos, R.P., Bebianno, M.J., Cabral, H.N., 2012. Application of an integrated biomarker response index (IBR) to assess temporal variation of environmental quality in two portuguese aquatic systems. Ecological Indicators, 19: 215-225. (doi:10.1016/j.ecolind.2011.08.009)